9E2J | pdb_00009e2j

Variediene synthase with five cyclases

PDB DOI: https://doi.org/10.2210/pdb9E2J/pdb
EM Map EMD-47454: EMDB EMDataResource

Classification: TRANSFERASE
Organism(s): Aspergillus stellatus
Expression System: Escherichia coli
Mutation(s): No

Deposited: 2024-10-22 Released: 2025-05-21
Deposition Author(s): Wenger, E.S., Christianson, D.W.
Funding Organization(s): National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

Experimental Data Snapshot

Method: ELECTRON MICROSCOPY
Resolution: 3.59 Å
Aggregation State: PARTICLE
Reconstruction Method: SINGLE PARTICLE

wwPDB Validation 3D Report Full Report

This is version 1.0 of the entry. See complete history.

Literature

Variediene synthase with five cyclases

Wenger, E.S., Christianson, D.W.

To be published.

Macromolecule Content

Total Structure Weight: 495.42 kDa
Atom Count: 25,560
Modeled Residue Count: 3,174
Deposited Residue Count: 4,350
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Variediene synthase	A, B, C, D, E A, B, C, D, E, F	725	Aspergillus stellatus	Mutation(s): 0 Gene Names: EvVS EC: 4.2.3.218 (PDB Primary Data), 4.2.3.219 (PDB Primary Data), 2.5.1.29 (PDB Primary Data), 2.5.1.81 (PDB Primary Data)
UniProt
Find proteins for A0A0P0ZD79 (Emericella variicolor) Explore A0A0P0ZD79 Go to UniProtKB: A0A0P0ZD79
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	A0A0P0ZD79
Sequence Annotations Expand
Reference Sequence

Experimental Data & Validation

Experimental Data

Method: ELECTRON MICROSCOPY
Resolution: 3.59 Å
Aggregation State: PARTICLE
Reconstruction Method: SINGLE PARTICLE

EM Software:

Task	Software Package	Version
MODEL REFINEMENT	PHENIX

Structure Validation

View Full Validation Report

Entry History & Funding Information

Deposition Data

Released Date: 2025-05-21

Deposition Author(s):

Christianson, D.W.

Funding Organization	Location	Grant Number
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)	United States	574961-0089

Revision History (Full details and data files)

Version 1.0: 2025-05-21
Type: Initial release

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.