Download MendeleySARS-CoV-2 papain-like protease (PLpro) C112S mutant
Camara-Artigas, A.To be published.
9F7R | pdb_00009f7r
SARS-CoV-2 papain-like protease (PLpro) C112S mutant
- PDB DOI: https://doi.org/10.2210/pdb9F7R/pdb
- Classification: VIRAL PROTEIN
- Organism(s): Severe acute respiratory syndrome coronavirus 2
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2024-05-04 Released: 2025-05-14
- Funding Organization(s): Other government
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.50 ?
- R-Value Free: 0.163 (Depositor), 0.144 (DCC)
- R-Value Work: 0.145 (Depositor), 0.146 (DCC)
- R-Value Observed: 0.146 (Depositor)
Starting Model: experimental
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wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Replicase polyprotein 1ab | 319 | Severe acute respiratory syndrome coronavirus 2 | Mutation(s): 1 Gene Names: rep, 1a-1b EC: 3.4.19.12 (PDB Primary Data), 3.4.22 (PDB Primary Data) |  | |
UniProt | |||||
Find proteins for P0DTD1 (Severe acute respiratory syndrome coronavirus 2) Explore P0DTD1 Go to UniProtKB: P0DTD1 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P0DTD1 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PO4 Query on PO4 | D [auth A] | PHOSPHATE ION O4 P NBIIXXVUZAFLBC-UHFFFAOYSA-K |  | ||
| GOL Query on GOL | C [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
| ZN Query on ZN | B [auth A] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.50 ?
- R-Value Free: 0.163 (Depositor), 0.144 (DCC)
- R-Value Work: 0.145 (Depositor), 0.146 (DCC)
- R-Value Observed: 0.146 (Depositor)
Space Group: P 32 2 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 82.821 | ¦Á = 90 |
| b = 82.821 | ¦Â = 90 |
| c = 133.845 | ¦Ă = 120 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| Aimless | data scaling |
| XDS | data reduction |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-05-14 Deposition Author(s): Camara-Artigas, A.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Other government | Spain | P20_00149 |
Revision History (Full details and data files)
- Version 1.0: 2025-05-14
Type: Initial release
