Download MendeleyCryo-EM Structure of EV-D68 Vaccine Candidate - A2 Subclade Virus-like Particle
Cheng, J., Krug, P.W., Lei, H., Moss, D.L., Huang, R., Lang, Z.C., Morton, A.J., Shen, C., Pierson, T.C., Zhou, T., Ruckwardt, T.J., Kwong, P.D.To be published.
9C4A | pdb_00009c4a
Cryo-EM Structure of EV-D68 Vaccine Candidate - A2 Subclade Virus-like Particle
- PDB DOI: https://doi.org/10.2210/pdb9C4A/pdb
- EM Map EMD-45179: EMDB EMDataResource
- Classification: VIRUS LIKE PARTICLE
- Organism(s): enterovirus D68
- Expression System: Homo sapiens
- Mutation(s): No
- Deposited: 2024-06-03 Released: 2025-05-21
- Funding Organization(s): National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)
Experimental Data Snapshot
- Method: ELECTRON MICROSCOPY
- Resolution: 2.43 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| VP1 | 296 | enterovirus D68 | Mutation(s): 0 |  | |
UniProt | |||||
Find proteins for A0A8D5ZMD3 (Human enterovirus D68) Explore A0A8D5ZMD3 Go to UniProtKB: A0A8D5ZMD3 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | A0A8D5ZMD3 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| VP0 | 317 | enterovirus D68 | Mutation(s): 0 |  | |
UniProt | |||||
Find proteins for A0A141B2D4 (Human enterovirus D68) Explore A0A141B2D4 Go to UniProtKB: A0A141B2D4 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | A0A141B2D4 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 3 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| VP3 | 247 | enterovirus D68 | Mutation(s): 0 |  | |
UniProt | |||||
Find proteins for A0A097BW19 (Human enterovirus D68) Explore A0A097BW19 Go to UniProtKB: A0A097BW19 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | A0A097BW19 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Experimental Data & Validation
Experimental Data
- Method: ELECTRON MICROSCOPY
- Resolution: 2.43 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
| Task | Software Package | Version |
|---|---|---|
| MODEL REFINEMENT | PHENIX | |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-05-21 Deposition Author(s): Cheng, J., Krug, P.W., Lei, H., Moss, D.L., Huang, R., Lang, Z.C., Morton, A.J., Shen, C., Pierson, T.C., Zhou, T., Ruckwardt, T.J., Kwong, P.D.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | United States | -- |
Revision History (Full details and data files)
- Version 1.0: 2025-05-21
Type: Initial release
