9QA4 | pdb_00009qa4

Drosophila melanogaster angiotensin converting enzyme homologue, AnCE in complex with WR dipeptide

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C [auth A]	SCOP2B Superfamily	Metalloproteases (zincins), catalytic domain	8032242	3001975	SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C [auth A]	PF01401	Angiotensin-converting enzyme (Peptidase_M2)	Angiotensin-converting enzyme	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth B], B [auth C]	TRP-ARG dipeptide	-	-	-
C [auth A]	Angiotensin-converting enzyme	peptidase activity catalytic activity, acting on a protein metallopeptidase activity hydrolase activity catalytic activity peptidyl-dipeptidase activity exopeptidase activity carboxypeptidase activity cation binding ion binding binding metal ion binding small molecule binding	sexual reproduction reproductive process developmental process multicellular organism development multicellular organismal process anatomical structure development metamorphosis peptide hormone processing regulation of hormone levels biological regulation signaling receptor ligand precursor processing primary metabolic process gene expression macromolecule biosynthetic process sexual reproduction reproductive process developmental process multicellular organism development multicellular organismal process anatomical structure development metamorphosis peptide hormone processing regulation of hormone levels biological regulation signaling receptor ligand precursor processing primary metabolic process gene expression macromolecule biosynthetic process hormone metabolic process protein maturation biosynthetic process proteolysis protein processing metabolic process cellular process amide metabolic process protein metabolic process macromolecule metabolic process regulation of biological quality response to symbiont biological process involved in interspecies interaction between organisms response to stimulus response to other organism response to bacterium response to symbiotic bacterium response to external stimulus response to external biotic stimulus response to biotic stimulus	cell periphery cellular anatomical structure plasma membrane membrane extracellular region extracellular space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C [auth A]	IPR001548	Peptidase M2, peptidyl-dipeptidase A	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.