273-4D01 Fab in complex with HIV-1 BG505 SOSIP Env trimer and RM20A3 Fab
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
A [auth L] | Light Chain | IGKV1 | Kappa | hiv-1 envelope glycoprotein bg505 sosip.664 gp120 | SAbDab (2025-05-23) |
D [auth G], H [auth J], L [auth M] | Heavy Chain | IGHV3 | - | envelope glycoprotein gp160, envelope glycoprotein gp160 | hiv-1 envelope glycoprotein bg505 sosip.664 gp120 | SAbDab (2025-05-23) |
E [auth I], I [auth K], M [auth N] | Light Chain | IGLV2 | Lambda | envelope glycoprotein gp160, envelope glycoprotein gp160 | hiv-1 envelope glycoprotein bg505 sosip.664 gp120 | SAbDab (2025-05-23) |
N [auth H] | Heavy Chain | IGHV1 | - | hiv-1 envelope glycoprotein bg505 sosip.664 gp120 | SAbDab (2025-05-23) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
B [auth A], F [auth C], J [auth E] | PF00516 | Envelope glycoprotein GP120 (GP120) | Envelope glycoprotein GP120 | The envelope glycoprotein Gp160 of HIV1 is cleaved into the surface protein Gp120 and the transmembrane protein Gp41. The entry of HIV requires interaction of viral GP120 with the CD4 glycoprotein (Swiss:P01730) and a chemokine receptor on the cell s ... | Domain |
C [auth B], G [auth D], K [auth F] | PF00517 | Retroviral envelope protein (GP41) | Retroviral envelope protein | - | Family |