Download MendeleyHuman carbonic anhydrase II complexed with 2-hydroselenobenzoic acid
Angeli, A., Ferraroni, M.To be published.
9FAI | pdb_00009fai
Human carbonic anhydrase II complexed with 2-hydroselenobenzoic acid
- PDB DOI: https://doi.org/10.2210/pdb9FAI/pdb
- Classification: LYASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2024-05-10 Released: 2025-05-21
- Funding Organization(s): Not funded
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.27 ?
- R-Value Free: 0.152 (Depositor), 0.163 (DCC)
- R-Value Work: 0.113 (Depositor), 0.130 (DCC)
Starting Model: experimental
View more details
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Carbonic anhydrase 2 | A [auth AAA] | 260 | Homo sapiens | Mutation(s): 0 Gene Names: CA2 EC: 4.2.1.1 (PDB Primary Data), 4.2.1.69 (UniProt) |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P00918 (Homo sapiens) Explore P00918 Go to UniProtKB: P00918 | |||||
PHAROS: P00918 GTEx: ENSG00000104267 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P00918 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| A1IBT (Subject of Investigation/LOI) Query on A1IBT | E [auth AAA] | 2-selanylbenzoic acid C7 H6 O2 Se UYXHJPFMESJIIY-UHFFFAOYSA-N |  | ||
| ZN Query on ZN | D [auth AAA] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
| EDO Query on EDO | B [auth AAA] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
| ACT Query on ACT | C [auth AAA] | ACETATE ION C2 H3 O2 QTBSBXVTEAMEQO-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.27 ?
- R-Value Free: 0.152 (Depositor), 0.163 (DCC)
- R-Value Work: 0.113 (Depositor), 0.130 (DCC)
Space Group: P 1 21 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 42.39 | α = 90 |
| b = 41.31 | β = 104.139 |
| c = 72.61 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| XDS | data reduction |
| XSCALE | data scaling |
| REFMAC | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-05-21 Deposition Author(s): Angeli, A., Ferraroni, M.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Not funded | -- |
Revision History (Full details and data files)
- Version 1.0: 2025-05-21
Type: Initial release
