Download MendeleyStructure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH13677
Scaletti, E., Stenmark, P.To be published.
9F8Z | pdb_00009f8z
Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH13677
- PDB DOI: https://doi.org/10.2210/pdb9F8Z/pdb
- Classification: DNA BINDING PROTEIN
- Organism(s): Mus musculus
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2024-05-07 Released: 2025-05-21
- Funding Organization(s): Cancerfonden
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 ?
- R-Value Free: 0.277 (Depositor), 0.277 (DCC)
- R-Value Work: 0.225 (Depositor), 0.225 (DCC)
Starting Model: experimental
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This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| N-glycosylase/DNA lyase | 318 | Mus musculus | Mutation(s): 0 Gene Names: Ogg1 EC: 3.2.2 (PDB Primary Data), 4.2.99.18 (PDB Primary Data) |  | |
UniProt | |||||
Find proteins for O08760 (Mus musculus) Explore O08760 Go to UniProtKB: O08760 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | O08760 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| A1IBJ (Subject of Investigation/LOI) Query on A1IBJ | D [auth A], G [auth B] | ~{N}4-(5-chloranyl-6-methoxy-pyridin-3-yl)-1~{H}-pyrazolo[3,4-d]pyrimidine-4,6-diamine C11 H10 Cl N7 O LSTTVYOLIIXOOG-UHFFFAOYSA-N |  | ||
| SO4 Query on SO4 | F [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| NI Query on NI | E [auth A] | NICKEL (II) ION Ni VEQPNABPJHWNSG-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.50 ?
- R-Value Free: 0.277 (Depositor), 0.277 (DCC)
- R-Value Work: 0.225 (Depositor), 0.225 (DCC)
Space Group: P 21 21 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 80.643 | ¦Á = 90 |
| b = 82.369 | ¦Â = 90 |
| c = 171.967 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| XDS | data reduction |
| STARANISO | data scaling |
| MOLREP | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-05-21 Deposition Author(s): Scaletti, E., Stenmark, P.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Cancerfonden | Sweden | -- |
Revision History (Full details and data files)
- Version 1.0: 2025-05-21
Type: Initial release
