Download Mendeleyhuman citrate synthase complexed with citrate
Yang, L.Y., Fang, Y.J.To be published.
8ZVV | pdb_00008zvv
human citrate synthase complexed with citrate
- PDB DOI: https://doi.org/10.2210/pdb8ZVV/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2024-06-12 Released: 2025-06-18
- Funding Organization(s): National Natural Science Foundation of China (NSFC)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.59 ?
- R-Value Free: 0.295 (Depositor), 0.299 (DCC)
- R-Value Work: 0.241 (Depositor), 0.248 (DCC)
- R-Value Observed: 0.244 (Depositor)
Starting Model: experimental
View more details
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Citrate synthase, mitochondrial | 434 | Homo sapiens | Mutation(s): 0 Gene Names: CS EC: 2.3.3.1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for O75390 (Homo sapiens) Explore O75390 Go to UniProtKB: O75390 | |||||
PHAROS: O75390 GTEx: ENSG00000062485 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | O75390 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| CIT Query on CIT | E [auth A], F [auth B], G [auth C], H [auth D] | CITRIC ACID C6 H8 O7 KRKNYBCHXYNGOX-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.59 ?
- R-Value Free: 0.295 (Depositor), 0.299 (DCC)
- R-Value Work: 0.241 (Depositor), 0.248 (DCC)
- R-Value Observed: 0.244 (Depositor)
Space Group: P 1 21 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 57.548 | ¦Á = 90 |
| b = 194.332 | ¦Â = 90.4 |
| c = 69.369 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| XDS | data reduction |
| XDS | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-06-18 Deposition Author(s): Yang, L.Y., Fang, Y.J.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Natural Science Foundation of China (NSFC) | China | -- |
Revision History (Full details and data files)
- Version 1.0: 2025-06-18
Type: Initial release
