Download MendeleyMagnesium Ion Locking RhoA Mutant in Highly Dynamic Cycling Conformations
Wu, H., Jiang, H.To be published.
8ZNY | pdb_00008zny
Small GTPase RhoA Y42C mutant in complex with GDP
- PDB DOI: https://doi.org/10.2210/pdb8ZNY/pdb
- Classification: CELL INVASION
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2024-05-28 Released: 2025-06-04
- Funding Organization(s): National Natural Science Foundation of China (NSFC)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.65 ?
- R-Value Free: 0.217 (Depositor), 0.217 (DCC)
- R-Value Work: 0.183 (Depositor), 0.183 (DCC)
Starting Model: experimental
View more details
This is version 1.0 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Transforming protein RhoA | 182 | Homo sapiens | Mutation(s): 1 Gene Names: RHOA, ARH12, ARHA, RHO12 EC: 3.6.5.2 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P61586 (Homo sapiens) Explore P61586 Go to UniProtKB: P61586 | |||||
PHAROS: P61586 GTEx: ENSG00000067560 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P61586 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| GDP (Subject of Investigation/LOI) Query on GDP | B [auth A] | GUANOSINE-5'-DIPHOSPHATE C10 H15 N5 O11 P2 QGWNDRXFNXRZMB-UUOKFMHZSA-N |  | ||
| MG (Subject of Investigation/LOI) Query on MG | C [auth A] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.65 ?
- R-Value Free: 0.217 (Depositor), 0.217 (DCC)
- R-Value Work: 0.183 (Depositor), 0.183 (DCC)
Space Group: P 21 21 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 32.14 | ¦Á = 90 |
| b = 64.06 | ¦Â = 90 |
| c = 82.37 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| PDB_EXTRACT | data extraction |
Entry History & Funding Information
Deposition Data
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Natural Science Foundation of China (NSFC) | China | -- |
Revision History (Full details and data files)
- Version 1.0: 2025-06-04
Type: Initial release
