Download MendeleyStructure of 3-amino-3-carboxyltransferase in complex with SAH and nocardicin G in the biosynthesis of nocardicins
Gao, Y., Mori, T., Awakawa, T., Abe, I.To be published.
8ZHV | pdb_00008zhv
Structure of 3-amino-3-carboxyltransferase in complex with SAH and nocardicin G in the biosynthesis of nocardicins
- PDB DOI: https://doi.org/10.2210/pdb8ZHV/pdb
- Classification: TRANSFERASE
- Organism(s): Nocardia uniformis subsp. tsuyamanensis
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2024-05-11 Released: 2025-05-14
- Funding Organization(s): Not funded
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.13 ?
- R-Value Free: 0.230 (Depositor), 0.225 (DCC)
- R-Value Work: 0.182 (Depositor), 0.180 (DCC)
- R-Value Observed: 0.185 (Depositor)
Starting Model: in silico
View more details
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Isonocardicin synthase | 326 | Nocardia uniformis subsp. tsuyamanensis | Mutation(s): 0 Gene Names: nat, nocC EC: 2.5.1.38 |  | |
UniProt | |||||
Find proteins for Q9RAH6 (Nocardia uniformis subsp. tsuyamanensis) Explore Q9RAH6 Go to UniProtKB: Q9RAH6 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9RAH6 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| A1L1U (Subject of Investigation/LOI) Query on A1L1U | D [auth A], F [auth B] | Nocardicin G C19 H19 N3 O6 SAVAPYNOQXYBJS-JYJNAYRXSA-N |  | ||
| SAH (Subject of Investigation/LOI) Query on SAH | C [auth A] | S-ADENOSYL-L-HOMOCYSTEINE C14 H20 N6 O5 S ZJUKTBDSGOFHSH-WFMPWKQPSA-N |  | ||
| A4D Query on A4D | E [auth B] | 5'-thioadenosine C10 H13 N5 O3 S HLJHWWUZHBUUAC-KQYNXXCUSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.13 ?
- R-Value Free: 0.230 (Depositor), 0.225 (DCC)
- R-Value Work: 0.182 (Depositor), 0.180 (DCC)
- R-Value Observed: 0.185 (Depositor)
Space Group: P 21 21 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 48.221 | ¦Á = 90 |
| b = 76.582 | ¦Â = 90 |
| c = 146.758 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| Aimless | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-05-14 Deposition Author(s): Gao, Y., Mori, T., Awakawa, T., Abe, I.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Not funded | -- |
Revision History (Full details and data files)
- Version 1.0: 2025-05-14
Type: Initial release
