DrugBank ID DB00878 ? Name Chlorhexidine Groups vet_approved withdrawn approved Description Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.[L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today.[A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain.[A190453] Topical chlorhexidine for disinfection, as well as oral rinses for dental use, carries activity against a broad range of pathogens including bacteria, yeasts, and viruses.[L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the early 1950s[A190474] and was introduced to the US in the 1970s.[L11572] The FDA withdrew its approval for the use of chlorhexidine gluconate topical tincture 0.5%, due to a significant number of reports concerning chemical and thermal burns associated with the use of this product.[L43942,L44027] Other formulations of chlorhexidine continue to be available. Synonyms Chlorhexidine gluconate Clorhexidina Chlorhexidine hydrochloride Chlorhexidinum Chlorhexidine
1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide) Cloresidina Chlorhexidine acetate N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide Chlorhexidin more Brand Names Steri-stat Tincture (tinted) Antis Prep Gel PMS-chlorhexidine 3M Avagard BD E-Z Scrub Oris Chx
Surgical and healthcare personnel hand antiseptic with moisturizers Chlorhexidine-cetrimide Soltn Conc ReadyPrep CHG Sanital Antibacterial Hand Soap Dr. Zheng s acteriostatic gel Antiseptic Skin Cleanser Exidine-2 CHG Prevantics Swabstick Baxedin Spectro Gram 2 Skin Cleanser Jisberry Hand Sanitizer Flamazine C Akilgeld Hand Sanitizer Bactoshield Chg 4% Oral Cleansing and Suctioning System, q2 Disinfectant Wet Tissues Hand Sanitizer Gel Biokaab NuSurgePak Surgical Prep/CarePak Tai Yu Ling Antibacterial Sprays 10mL Pre-moistened Towelette Dermawerx Surgical PrePak Chlorhexidine Gluconate, 0.12% Oral Rinse Solution Bactoshield CHG Smart San CHG WhyteDerm SurgiPak Oro-clense Hand Sanitizer Prevantics Swab Chlorhexidine Gluconate 0.12% Oral Rinse, USP Liszt Hand sanitizer without washing Loris I.V. Pro - Swabstick Chlorhexidine and Isopropyl Alcohol Swabsticks Cida-stat Foam Salvesept Crm Periogard Soluprep AQ Wipe Provon Antimicrobial Foam Handwash Endure 420 Cida-Stat Skinvisible Chlorhexidine Formula Hand Sanitizer Lotion HandSoap Quick-Drying Hand Sanitizer DEQGEL Advanced Hand Sanitizer Bioprep Liq Soluprep Applicator Motherwort Herb Feminine Antibacterial Gels Loris - I.V. KIMVENT ORAL CARE Q4 Kit WITH CHG Chlorhexidine Liq 0.05% Loris I.V. Pro - Sponge Antiseptic Solution Disinfectant Spray(Speedy effect type) Hibiclens Antiseptic/antimicrobial Skin Cleanser Surgical Continuum System Scrub Care Surgical Scrub Brush/nail Cleaner With Exidine 4 Kimvent Oral Care Q2 Kit with CHG Spray On Plastic Bandage Aerosol Periogard (Chlorhexidine Gluconate) Calgon Vestal 4% Chg Antimicrob.skin Cleans. Chlorhexidine and Isopropyl Alcohol Prep Pads Sunberry Rinse free Hand Sanitizer Steri-stat Liq 2.0% Euro-chlorhexidine X-pur Chlorhexidine Soluprep AQ Sponge QCare Rx Oral Cleansing and Suctioning System, Q2 Steri-clean Chlorhexidine gluconate NUPRO Chlorhexidine Gluconate Major Oral Rinse Scrub Chlorhexidine Gluconante Chlorhexidine 2% Antiseptic Hand Wash Baxedin 2% - 70% Chlorhexidine Gluconate, 0.12% Oral Rinse Foaming Chlorhexidine Gluconate Liquivida Hydration Endure 400 Scrub-Stat 4 Burn O Sol Spray Steri-stat Liq 20% Wart Remover Ointment. Bactoshield Antiseptic Lotion Soap 2% Soluprep Qd Swab Laura Line Chlorhexidine Antiseptic Soap Hygenipak 2% Chg Foaming Skin Cleanser Soluprep Antiseptic Skin Cleanser Sponge B-good Hand and Skin Disinfecting Agent Rouhex G Liq 2% Purell Antimicrobial Foam Zedoary Oils Feminine Antibacterial Gels Scrub Stat 4 Foam Liq Microban Medical Hibiclens PS2 Aciurgy Pack Pre-Scrub II Surgical Hand Scrub CliniClean Baxedin Pre-OP Germi Stat Gel 2% Antiseptic Skin Cleanser Acclean Chlorhexidine Gluconate 0.12% Oral Rinse Noble 75% Alcohol Wipes Scrub-stat IV 4% Solunet C Brosse 4% QCare Rx Oral Cleansing and Suctioning System, Q4 Dexidin 2 Detergent Peridex Mlk F4-C Hygienipak 4% Chg Foaming Skin Cleanser Antiseptic Cleanser Solution Purell CS Foam Handwash 2% CHG Provon Antiseptic Lotion Soap With 2% Chg Loris 2% Chg Body Cleanser/nettoyant Pour Le Corps Peridex Oral Rinse Dyna-hex 4 Oronine H Ointment 1% Chlorhexidine DermacinRx Surgical PharmaPak Chinese Herb Essence Bacteriostatic Feminine Wash Hibiclens for Georgia Pacific Stat Touch 2 Antimicrobial Skin Cleanser Freeman Packing Alcohol Wipe Scrub Care Exidine-2 CHG Chlorhexidine Alcohol Free Bacti-stat Chg Rouhex G 20% Serdaen Septi-san Q2 Oral Care Kit with CHG Bactoshield CHG Chlorhexidine Gluconate Avidene Surgical Scrub Hibitane Skin Cleanser Liq 4% Prevora Stage 1 Betasept Prevantics swabstick Foaming Hand Antiseptic With Chg 2% Soluprep AQ Chlorhexidine Gluconate Solution 0.05% Savlon Hospital Concentrate Aplicare Chlorhexidine Gluconate 2% Solution Plant Herb Based Bacteriostatic Feminine Wash Denti-Care Denti-Rinse Chlorhexidine Gluconate Oral Rinse Gum Paroex Antiseptic Body Cleanser Aplicare Antiseptic Chlorhexidine Gluconate Scrub Care Foaming Hand Wash Bactoshield CHG Chlorhexidine Gluconate Solution Halyard Chlorhexidine Gluconate Periogard Alcohol Free QCare Rx Oral Cleansing and Suctioning System E-Z Scrub 747 4% Antiseptic Cleansing Wipes Paroex Steri-stat Liq 4.0% Calgon Vestal 2% Chg Antimicrob.skin Cleans. Quick-drying rinse-free hand skin disinfectant Seaqua X Rouhex G 4% Soluprep Ld Sponge Antimicrobial Skin Cleanser Rugby Antiseptic Skin Cleanser Smart Sense Antiseptic Skin Cleanser SANIDEP Advanced Sanitizer with Organic Extracts Denticare Chlorhexidine Gluconate Oral Rinse 0.12% Scrub-Stat E-Z Scrub Antimicrobial Foam Solution Containing 4% Chg Prevantics Maxi Swabstick Hygenipak 2% Chg Skin Cleanser Sterixin 0.05% Antiseptic First Aid Spray Baxedin Liq 20% Wart removal 3M SoluPrep S Chlorhexidine Gluconate Oral Rinse Dexidin 2 Solution Chloraprep Swabsticks Spectro Tar Antiseptic Shampoo Hibidil DermacinRx Surgical ComboPak Anti-bac Hand DASH Chlorhexidine Gluconate 0.12% Oral Rinse Antiseptic Foam Handwash Soluprep Bioprep Stanhexidine Aqueous 2% With 4% Isopropyl Alcohol Hexifoam-skin Disinfectant Aer 1% Germi-stat 0.5% Antiseptic Prep Gel Betalido-C BD E-Z Scrub 107 Ic-gel Avagard Chg Hibitane Skin Cleanser Cardinal Health Antiseptic Skin Cleanser PhysiciansCare Eyewash Station Additive Concentrate Maxiclens Chlorhexidine gluconate Liquid Solution, 4% Hibitane Skin Cleanser 4% Henry Schein Antimicrobial Skin Cleanser Skin antisepsis, oral cleansing, nasal antisepsis Selpak Antibacterial Wet Wipes Laura Line Antibacterial Cream Soap 2% CLIP Liquid Sanitizer ICEKING Skin Expert Refreshing Body Roller Loris I.V. Pro - Prefilled Applicator With Solution Stanhexidine Red Tincture 0.5% Hibitane Skin Cleanser 2% Soft Care 2% Chg Antimicrobial Skin Cleanser 3M SoluPrep Gelato Chlorohexidine 3m Soluprep Sponge Hand wipes Soluprep AQ Swab Chlorhexseptic-liq 0.5mg/ml Zappy Ultimate Antiseptic Wipes Soluprep Antiseptic Skin Cleanser Preoperative Kit Hygienipak 4% Chg Skin Cleanser Cardinal Health Foster and Thrive Soluprep AQ Applicator Hibistat Ostar Antimicrobial Hand Soap 2% - Liquid Dermsafe Pc Pro-dentx Chlorhexidene Oral Rinse Akilspray Hand Sanitizer Anti Mucedine Feminine Wash Sky Oral Rinse Rougier Clean Derm Oral Cleansing and Suctioning System, q4 Chlorhexidine 4% Antiseptic Hand Wash JIANLIANG Antibacterial Sprays 10mL Ezy-TM Scrub Care Exidine -4 CHG Medifresh Hand Skin Antiseptic Disinfectant Wet Wipes Chlorhexidine 0.5% Liq Bactoshield Chg 2% Dexidin 20 Foam Safe Dr. Luke Molluscum Wart Remover Yu Ding Antibacterial Sprays 10mL Germi-stat 2% Foaming Liquid Spray On Plastic Bandage Non-aerosol ChloraPrep One-Step SAITENM Health Wet wipes Dyna-Hex 4 Dr. Luke Wart Remover Soluprep Qd Solution ChloraPrep Swabstick Dermsafe Chlorhexidine Gluconate Hand Sanitizer Lotion Dexidin 0.5 Solution Foam Care Chg Surgical Hand Scrub Chloraprep Dyural 80 LM-C Chlora-cleanze QCare Rx Petite Oral Cleansing and Suctioning System Loris 2% Chg Wipe/serviette Hands-free skin sanitizer Dyna-hex 2 Rougier Vap-chlorhexidine Gluconate 2% W/V Soluprep Qd Wipe Antimicrobial Foam Handwash Eyewash Station Additive Concentrate Pre and Post Sx Pouch E-Z Scrub 107 LARA MED Antibacterial Wet Wipes Loris 2% Chg Solution Alcohol Antibacterial Wipes Wart Removal Pen HYDROGEL ESSENCE Antimicrobial Virginal Gel. Stanhexidine 2% With Isopropyl Alcohol 4% PMS-chlorhexidine Without Alcohol Chlorhexidine Gluconate Applicator Savlodil Hand Sanitizer Biokaab Antibacterial Protective Hand Perioselect Antimicrobial Sol 0.12% Protective Hand Ultrastat Chloraprep Liq 0.5% First Aid Antiseptic Skin Cleanser Germi Stat Gel 4% Hygienium Instillagel Cida-stat Liq Dexlido M-C Purmist Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System Hibistat Germicidal Hand Rinse Stanhexidine 20% Bei Ling Tong Bao Er Zheng Yuan Antibacterial Creams Maxiclens Chlorhexidine Gluconate Liquid Solution, 4% Hexirex Antiseptic Skin Cleanser Dermawerx Surgical Plus Pak DermacinRx Clorhexacin Purell Antimicrobial Foam Handwash 2% Chg Dr. Dean Germi-stat Prep Gel (Fruli) Quick-Dry Disposable Hand Sanitizer Alcohol Disinfectant Wipes (Qiqing) Chlorhexidine Gluconate Alcohol Disinfectant Chlorhexidine Gluconate 0.12% Oral Rinse PerioChip Disinfectant Fabric Wash Hexicinide Soluprep Wipe Stanhexidine 4% With Isopropyl Alcohol 4% Chlorhexidine Gluconate Solution USP 20% Dyna-Hex 2 Oro Clear Peridex Oral Rinse 0.12% CleanCare Chlorhexidine Gluconate 0.12% Oral Rinse Bactigras Dyna-Hex 75 Dyural LM- C Soft Care Antiseptic Hand Soap PS1 Aciurgy Pack Sterigel Plus Chlorhexidine Solution KleerSight Scrub, Scrub-Stat, Foam Safe, Micro-Guard Dexidin Liq 4% Soluprep Swab Scrub, Scrub-Stat Chlorhexidine Gluconate Solution 0.75% Antiseptic Hand Wipes Chlorhexidine Gluconate Hospicare 40R Adult Body Wipes more Indication Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures.[L11518,L11521,L11527,L11533] Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis[L11512] and a slow-release "chip" which is inserted into periodontal pockets and is indicated for the reduction of pocket depth in adult patients with periodontitis as an adjunct therapy to dental scaling and root planing procedures.[L11536] Categories Alimentary Tract and Metabolism Amidines Anti-Infective Agents Anti-Infective Agents, Local Antiinfectives and Antiseptics for Local Oral Treatment
Antiseptics and Disinfectants Biguanides Biguanides and Amidines Compounds used in a research, industrial, or household setting Decreased Cell Wall Integrity Dental Agents Dermatologicals Disinfectants Guanidines Household Products Irrigating Solutions Medicated Dressings Medicated Dressings With Antiinfectives Miscellaneous Anti-infectives Miscellaneous Local Anti-infectives Mouthwashes Mouthwashes and Gargles Ophthalmological and Otological Preparations Ophthalmologicals Otologicals Sensory Organs Stomatological Preparations Throat Preparations more ATC-Code more CAS number 55-56-1 
