VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152 ?
Name	Thiamine
Groups	vet_approved nutraceutical approved investigational
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Antiberiberi factor Thiamine mononitrate thiamine(1+) ion Thiaminum Thiamine chloride Tiamina Aneurin Thiamine thiamine(1+) thiaminium Thiamin Thiamine hydrochloride Vitamin B1
Brand Names	Quflora Pediatric B-complex 100 Tricare Prenatal 2-part Daily Prenatal Vitamin System Multivit with Fluoride Mvc PM Caps Folic-K Pnv Ob DHA Multivitamin Drops with Fluoride Vital-D Rx Multi-Vit-Flor Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA B With C 500 Cap Stress Forte Plus Lipotropic Factors Vimeral Tab Tricare Prenatal Quick Dissolve Dia-vite Multi Plex II - Tab Vitogen B Stress C Vit E Zinc & Cop Totalvit Plus Vitamin B Complex 50 CompleteNate Chewable Stresstabs + Zinc-copper Se-Plete DHA Adult Infuvite Multiple Vitamins Childrens Chewable Tab B Complex W C Forte Cap Children's Chewable Multi-vitamin Children's Chewable Multi-vitamin Complete With Minerals TriStart DHA Vita Plex Tab Multivitamin with fluoride Quflora Pediatric Drops Children's Chewable Multi Vit W Iron Isotonix Multitech Vitamin Mineral Supplemen Duet DHA Cedevita Sugar-free Vitamin Supplement Vitamin B1 Tab 2mg USP Twin G.F. Powder Vanilla Flavor Bugs Bunny Chew Multi Vit Plus Iron Renal Caps Dialysis/Stress Vitamin Supplement Supravite C 1000 Viva CT Prenatal Tonicol Et A-D-C Ampoules/comprimes WesCap-C-DHA Prometa Vol-Tab Rx Card-floe II Tab Vitaday Tab L.C. Supplement Revit Tab Multivitamins W Iron FloraFol For Kids Only Chewable Multivitamins Multivitamin & Multimineral Vitamin B Compound W Vit C 250mg Tab Multiple Vitamins W Minerals Tab Hi Potency Stress B Tension With C Multivitamins Prevital Tab PNV-First Dialyvite 3000 Supravite 10ml Ampoule Twin Ultra Liquid Fruit Punch Flavor Prenatrix Multi-Vitamin Drops with Fluoride and Iron Mangadyn Nutra-Z Obstetrix DHA Combo Pack Phytopure TL-Care DHA Multivitamins and Multiminerals Formula Regular Tablet Vitamin B Complex 100 Azesco Livron Plus Tab V & M Vitamin and Mineral Supplement Vitamin B1 100mg Tablet Vitamines Pour Bebes Et Enfants Davimet-M Mvc 9+4 Inj Vita-B-75 Cap NeuroBion Super Pantoplex Multi Vitamin Drops with Fluoride Vitafant Thiamine B1 Tab 100mg THIAMINE HCl Vitafol One Nutra Boost Multivitamin with Fluoride Distilpure Msm AzesChew Complete Multivitamins and Minerals Tablets Timed Release Select OB Hyporyl - Tab Neonatal Vitamin Xvite Children Choice Multivitamin W Iron Chew Tab Swiss Total One Virt-Vite Plus Amladex Balanced B-100 Timed Release Irospan 24/6 Kanga-kid Multi-vitamin & Mineral B C Antistress Cap Formula Gly Multi-Vitamin Revitex Ampoules Et Comprimes Strovite Forte Caplet P.N. Vitamin-mineral Drink VitaPhil Aide Complete-RF Prenatal Multivitamines Plus Fer Pour Enfants (chewable Tablets) PNV Ferrous Fumarate Docusate Folic Acid Prenatal, DHA OB Complete 400 One Daily Vitamin and Mineral Dietary Supplement G.A.S. Complex Gesticare DHA Pregnancy Multivitamin Children's Chew Multi & Min Tab 50 Plus Thrivite 19 Derma-force Maximum Once A Day Penta-thion Pwr Childrens Chewable Multivitamins W Iron Livita Adults Vita-vim - Tab B Vitamin Compound With B12 Thunas Nutri-Tab OB plus DHA Super Vitalex Ampoule Buvable Thiamine HCl 100mg W C 20mg Vinacal TRONVite Twin Ultra Liquid Orange Flavor Formula Pro-B Balanced B-50 B-complex Vitamins Tab Dalivit Supravite Stress Avec Vit E Et Fer Surbex 500 Filmtab NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Vitaplex Innersource Tab Stressmates Corvite Free Somavit Brand Vitamins and Minerals Complex Alertonic Tonimol Cap Liq Natal PNV Infuvite Pediatric Men's Pregnancy Multivitamin Folic 5 Floravit - Syr Multi Vitamin Drops with Fluoride with Iron Multi Enfants Tab MultiVitamin Drops with Fluoride and Iron Prenatryl Prenatal Plus Multivitamin Plus DHA MiniCaps Tendera-OB Vigo Multivitamins Drops/lozenge Childrens Multiple Vit and Min Chew Tab Vitogen B Stress C600 Virt-Pn Multiple Vitamins and Minerals Capsules Twin Ultra Liquid Grape Flavor Multi-vitamins Vitamin B Compound With Vitamin C Fortis Capsule Dtc Vitamin B1 100 mg Original Bioscal Forte Multi-vitamin Supplement Capsules Chela Iron Plus C,b Complex Ribotin-E RayaVit Thiamine HCL 100 mg Zatean-Pn Liqui B Complex DaVITE Childrens Chewable Vitamin Tab NovaFerrum Multivitamin with Iron Pediatric Drops Super Vita Vim Multivitamins and Minerals Vitafol Ultra L.G.I.T. Dermamed Nutrition for troubled skin Neomultivite Usana Megavitamin Tablets - Tab Integra Plus RenaPlex Vit B1 Ctr Srt 100mg Multivit-liq Vena-Bal DHA Essential Vitamins and Minerals Elite OB Prenatal Multivitamin Kindervites Multi II IV Vi Tab Stress B Capsules With Vitamin C Marnatal F RE Prenatal Multivitamin with Iron Bal-Care DHA M-Natal Plus Multiple Vitamin Tab Maintain Multiple Vitamin & Minerals Prena1 Vitamin & Mineral Formula 1 Dietary Supplement B-plus - Tab CitraNatal Rx Z Bec Tab Moms Choice Rx For Kids Only Chewable Multivit. Plus Iron Fizz Multivitamins for Kids W C Loz THIAMINE HYDROCHLORIDE injection, solution B-complex 50 Bacmin Folika-NC Multi Pro Multi Vite Liq Junior Vitranol healthy mamaBE WELL ROUNDED BE WELL ROUNDED Diaplex Children's Vitamins W Iron Chewable For-2 Genicin Vita-S Dayavite B Complex W Vitamin C Fortis Cap Myhephron Dialysis and Stress Supplement Revitalize Multi-vitamin and Mineral Complex Complexe B-75 Cavan Heme OB PureFe Plus Maxum Multi-vite Multivitamin & Minerals (iron Free) Virt-Advance Provida OB Rocky Mountain Multiple Vit and Min Mega Tab Vitafol Fe Plus Vyqua Multiple Vitamins Prim - Royal P.M.T. Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) B Complex With C 300mg Cavan Alpha Davimet Twin Opti Pwr Advanced B & T Formula Dialyvite Supreme D Vasculine TL-Folate Mega Plex IV - Pck Zalvit Multi-Vit with Fluoride and Iron Allbee C 800 Tab Folivane-OB Sopalamine 3b Plus Multi Nt-OX Chewable Multivitamins bioJET Liquid B Complex 50 Multi Spectrum - Tablet Se-Natal Maxi 10 Tab Vitamin B Complex Plus 300mg Vitamin C Men's 50+ Manganese 50mg Plus B1 & E Tab Vitamin B Complex Plus C 300mg Timed Release Vitamin B Complex W C Tab Vol-Nate CitraNatal Assure Forty Plus Vitamin Supplement Women's Biomultiple Vitamin and Mineral Supplement Supplement De Multivitamines Infusion Arome Fruits Rouges Vita Day Tab Somarexin and C 1000 Multra Plex Kenwood Liquid Supplement Hi Potency B Complex W Chelated Minerals Formula B Super Stress Mega B Plus 1000mg Vit C Tab Flintstones Multiple Vitamins Plus Iron Prena1 Plus PrePLUS Childrens Chewable Multiple Vitamins Plus Fe ahoSAN Vitamin B Cpd W Vit C Tab B 50 Capsules Complete Mega B Multiple Vitamin Plus Minerals Tab Prenate Star Folika-T B Complex Tablets Daily-Vite Swiss One Multi Vit & Chel Min Tab DuetDHA Complete Vitafer - Liq vitaMedMD Rx Plus Multivitamine Childrens Chewable Multivitamins Multi Vitamin Plus Iron Multi Vite Liq Adult Duet DHA 400 ec Obstetrix EC Men's Multi Master Formula Vitamin and Mineral Supplement - Liq Paramettes Chewable Multivitamins Plus Iron Folivane-Plus with Ascorbic Acid Precursors Pnv-OB-dha Dexatrim Tablets B Plus C 300mg Timed Release V-Natal Ultimate OB DHA Virt-Bal DHA Plus Children's Chewable Vit and Min Tab Foliflex MultiVitamin with Fluoride Relnate DHA Vitasure Right Choice A.M. Multi Formula - Caplet L-Methyl PNV DHA Toni Com Liq Classic Swiss One 10 Multivitamin and Mineral Tab Abavite Beminal With C Fortis Pws Opti-manganese + B1 + C Caplet Women's Formula Onccor Stress Formula Multi-B Comp + 500mg Vit C Cap Chewable Adult Multivitamins With Minerals Escavite Lq Vita-Rx Diabetic Vitamin Grand Master Formula Tab Multi Vitamin and Fluoride Daily Energy Brand B-complex Renate Vitaflex Dietary Suplement OB Complete Petite Paramettes Multivits Plus Iron Tab (teens) Cavan Folate OB Maltlevol 12 Liq VIL-Rx Vita Vim Multivitamins and Minerals Tab Multivitamines Et Mineraux Junior Regulier Ziphex Re Ob 90 DHA Vitafol Caplet Bewon Elixir 0.05mg/ml Century Complete Livron Plus Ampoule Replavite Chew.multiple Vits.with Extra C for Children High Potency Multivitamins & Minerals Caplets Vitamin B1 Super Vita-vim With Beta-carotene - Tab Multiple Vitamins Tab Trinatal GT Niva-Plus Multi Vitamin - Mineral Mega Capsules Lysamine Diet Supp Amp-tab Multi-Vitamin Fluoride Drops Paramettes Chewable Multivits With Iron Tab Ventrixyl Virt Vite GT Super-pote Vitamin Supplement Flinstones Multiple Plus Iron Se-Tan PLUS Stress B Complex With C, E & Iron Vitaphil 90 DHA TM-Vite RX Vitazyme Master Key Multi Vitamin Multi Mineral Formula 2 Reno Caps Vitamine B1 100 Mg - Tablet Zoo Chews Plus Iron Floradix Formula Liq Quflora FE Multiple Vitamins Plus Iron for Women B-Combo Children's Chewable Multiple Vitamins (chewable Tablets) Concept OB Hi Potency B52 B Complex Tab Stress Formula Vit B With C Complex Virt-PN Bewon Elixir Trinaz Chela-manganese 50 Plus Meplex T 750 P.R.O. Complex Twin Ultra Liquid Lemon-lime Flavor Alsimine W Vitamins A D B Complex W Vit C W Non-med Yeast&liver Tab Multivitamins and Minerals for Women Kid's Choice Children's Chewable Vitamins - Tab Multivitamins and Minerals Tablets Orifer F Efferlife Multivitamins and Minerals Prenatabs FA Vitamine 110 Liq Nutri-Tab OB Floriva Children's Chewable Multiple Vitamins - Tab O-Cal FA multivitamin CitraNatal DHA M.V.I. Paediatric B50 Complex Fortistress Tab Viamon Ampoules Et Comprimes Allbee With Vitamin C Cap Vitamin B Complex Tab Supravite Pour Enfants Supravite Bouteille 250ml Thiamine HCl Tab 50mg Zintrexyl-C Permathene-12 - Caplet Am Caps Multicaps Vitamin B Complex + C 300mg Cap Vit B Complex Ctr WesTab Plus Natalvirt 90dha Children's Chewable Multivitamin Complete With Minerals Swical-energy-2 Multi - N.T.O.x Formula - Tab Nitro Vites - Tab Swiss One Multivitamin and Mineral Caplet MultiVitamin with Fluoride Drops Premium Prenatal Preplus INATAL Ultra Thiamine HCl Inj 100mg/ml Vitamin B Complex W C 300mg Tab Vitamin B1 Tablets 100mg RenaPlex-D B-complex Folica BE Vasodyn Tab Vitrexyl plus Iron Super B Compound W 500mg Vit C Timed Release Vita-vim Srt TL-Fluorivite Stress Tab With Zinc, Copper and Vitamin E Liqui B Complex Plus Prenatol-M Cedevita Plus Vitamin Supplement Prenate Elite Thiamine HCl Injection - Liq 100mg/ml Vitramyn H.W. Children's Chewable Multi Vit & Mineral Thiamiject Injection - Liq Im IV 100mg/ml Virt-Tabs NovaMV Multivitamin Vitamin B Compound Tab Multinate DHA Extra Genicin Vita-Q B-100 Caps Prenatal Vitamins Plus Materna - Tab Iberet 500 HemeNatal OB plus DHA Thiamine Hydrochloride Inj 100mg/ml USP Vitaphil DHA VitaXyme Prenatal and Post Partum Supplement Thiamine Hydrochloride Inj 100mg/ml WesCaps Stress B Complex With C, E and Iron Tab Children's Chewable Multivitamin and Multimineral PR Natal 430 ec Multi-12/k1 Pediatric Senior Multi One Vitamin B-1 100 Mg Tablets Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) Formula Lf Dr. AVi MULTIVITAMIN with Zinc, Real Ginger, Lemon and Lemongrass Multiple Vitamins W Iron Tab Methaver Multi-vitamins With Minerals Iron Polysaccharides Folic Acid DHA Cavan Prenatal Fortamines-10 Comprimes B Complex With C 550mg M.V.I.-12 Cal M Tab Adeks Tablets Vita-Pac Only One - Tablet Cda-21 Vitamins With Non-medicinal Probiotic Complex B Totum 500 Vitamin B + C Cap Stress B&c Tab Multiple Vitamins and Minerals Tab One A Day Tab Multi-actin Natalvirt Ca Glyco Lite Ect Childrens Chewable Vitamins W Iron Tandem OB Polymine Avec Zinc Et Cuivre Spectrum 2 Cap Vitabanks Vitamin Tab Deriton B Complex 50 Vitamin Cap Prenatvite Complete Balanced B-50 B-complex Vitamins, Timed Rele Doctor's Choice Brand for Men PR Natal 430 Neonatal19 Prenara Super Kids Chewable Multivitamin Multimineral (chewable Tablets) One A Day Multiple Vit W Minerals Davimet with Fluoride PNV Prenatal Vitamin Surbex-500 With Zinc Multivitamin with 0.25 mg Fluoride Time Release B 100 Compound - Tablet Children's Chewable Multi Vitamins Multi-Vit with Fluoride DuetDHA Balanced Premium Prenatal - Tablets Floriva Plus Vege Swiss One Multivitamin W Chel Mins Tab VP-Vite Rx Bal-Care DHA Essential B Complex W C and B12 Inj O-Cal Prenatal Vitamin Orti B Balanced B50 Complex Surbex-500 With Iron Multivit Et Fer Ampoules Et Comprimes C-Nate DHA B-complex Tab Children's Multivitamins With Iron Sibergin B - Cap Multi-kid Multisol Beminal 500 Tab Swical-energy 3e Age Thiamine HCl Tab 100mg Strovite One Caplets B50 B Complex Tab C.R.T. X Multivitamin & Mineral Powder Mix Croq-vit Pour Enfants Vita Balance 2000 Vitamin B Complex + C 600mg Tab Orange Flavored Crystal Chews Tab Synergistic Manganese Capsules B Complex 500 Tab Viva Kids - Tab C-B Complex Pregvit Vasula Tab Infa Drops Multivitamins One Tablet Daily Mens Formula Multra With Iron Complete One-A-day - Tab Focalgin 90 DHA Provida DHA RE FAC-x tensioSAN Vita B + C 500 Tab Adeks - Dps Pro Hers Vanilla Vitrexate Xyzbac G Central-vite 18 Essential Prenatal Vitamins and Minerals Tablets Children's Multivitamins Antlerviron Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo MVC-Fluoride Betaxin Spectrum Performa Multivitamins and Minerals Tablets B-complex Tablets Vita-amine Cap 100mg Iron, Vit & Min Supp Vitamines Et Mineraux Fortamines 10 Capsules Fusion Plus Magnum-75 Vitamin and Mineral Supplement PNV-Select Concept DHA Hemarexin Liquid and Drinkable Ampoules Escavite Hemarexin Tab Multi #2 24 Multivitamins + Minerals Essential B Tablets TriAdvance Tricare Prenatal Body Rox Multi-force for Adults Tab Se-Natal 19 Chela Potassium Plus Flintstones W Extra C Tab Vitamines Et Mineraux Enfants 970 Chewable Multiple Vitamins for Children Multivitamins W Minerals Extra Strength Vitamin B1 Tab 100mg USP For Kids Only Chewable Multivitamins - Tab Vitamin B Compound W C Tab 500mg Mvc 9 Plus 3 Inj Multitam Formula F L W Neo Vites Tab Hemocyte Plus PNV Prenatal Plus Multivitamin Women's Change Formula B Complex 50+ Caplet Poly-Vi-Sol PR Natal 400 ec PureVit DualFe Plus Tricare Prenatal DHA One B-100 Hi Potency B Vitamins Tab Formula Hh Stress Complex 600 Avec Vit E Cuivre Zinc Multi Vitamin & Minerals Kanga-kid Vitamins & Iron Multinate DHA One A Day Advance Fem Nutrol-B-complex Vita Vim With Beta Carotene-caplet Tricare Prenatal Compleat FolaMed DHA PNV Prenatal Vitamin Plus Vitamin A Multi Rol B Stress C + Iron & Vite Mini-B Tab Multi-Vitamin with Fluoride Vitamin B-Complex Fem Time Tab Phytovim Cap Fortaplex Inj B-1 Caps 500mg Garfield Chewable Multivitamins Tab Megavites Tab Glyco-aide Tab Men's Biomultiple Vitamin and Mineral Supplement Soluvit N Multiple Vitamins - Tablet Super Multi Poly-VI-sol Drops Stress Formula Multivitamin Tablets USP Chela-chromium 200 Stress Formula Choice OB DHA Children's Chewable With Iron Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Vitamin B-1 Thiamine HCl 100mg E.S.T. Complex Children's Chewable Multi Vitamins With Iron Tablets Kanga-B Vitamin B Group + C Milltrium Senior Vitamin and Mineral Supplement Multitabs Paramettes Syrup Folitin-Z Complete One A Day Tab Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Mebolic Multiple Vitamins Plus Iron - Tab Vp-pnv-dha Formula D.S. Ultra Enerforce Avon Vitadvance Multi-kids Complete Folika-V Multiple Vitamins With Iron Enviroflex - Tab Multi Vitamin with Fluoride Neo-bex Injectable Novel Vita Complete Multivitamins and Minerals for Children Multivitamins and Minerals With Betacarotene Tablets B-100 Vitamin Supplement Poly-Vite/Iron Oral Solution Venexa FE Animal Shapes Dialyvite with Zinc M.V.I. Adult D'pantothenic Acid-B1-B2 Tab Materna-tab Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops B1 400mg Ctr Tab Betaxin Liq 100mg/ml B Complex 25mg Vitamin Supplement B Complex Plus C 300mg Tab B-complex With Vitamin C, Biotin, Folic Acid Multivitamin Balanced B100 Balanced B 125 Srt Extra Once A Day Revit Plus Cap Virt Nate Vp-heme Ob B 6 Plus Paramettes Adults Nutrifer Plus Tablets Multivitamins and Minerals for Men Nephrocaps-QT SetonET Hormodausse Plus Calc Et D Tab Lipo-B-C Tab Hi Potency Multi Tab Maxi 6 Liq Foltabs Prenatal Osteo-force Vol-Plus Multi B Prenatal Multi Vitamin-mineral Formula Thiamine Hydrochloride Injection USP, 100mg/ml Paire OB Plus DHA Prenatal Plus Iron Prenatal Formula Tab Dexatran Potassium Plus Vit B Complex Stress Tab Carbassist Tablets Thiamine Hydrochloride Injection, USP Vitamin B1 Tab 100mg Olympian Multi Vit Plus Minerals Tab C. Vit-min Formula Multiple Vitamins With Iron Tablets Multivitamins and Minerals for Young Women Oncovite Extra P.N. Vitamin-mineral Drink Mix Folica-V Poly Vi Flor Chewable Tab Stress B-complex Plus Iron With Vitamins C&e Liqui Infant Vitamins Poly-Vi-Flor Kanga-V Multivitamins & Minerals Vitranol Fe Hylavite Multi Vitamin Drops with Fluoride and Iron Natavite Revit Multi-vitamins and Minerals Complex 5 - Pwr NEONATAL Complete Vitamin B Tablets Dothelle DHA Dexivite Prenatal Plus OB Complete Prenatal Super Daily No 2 Supravite Stress Avec Vit E Cuivre Et Zinc PreNatal Vitamins Plus Prenatal Vitamins Plus Low Iron Tricare Prenatal DHA One Rx Multivitamin Multivitamins and Minerals - Complete NataFort Childrens Chewable Vitamins Timed Release B-complex 100 Virt-Nate DHA Vita B Complex Tab Vitamine B1 Tab 100mg USP Prenatal Vi-min Vit-HA Multi Vitamin and Zinc Supplement Sopalamine/3b Plus C Swiss One Chewable Multiple Vitamins Plus Iron Tab Daily Balance Tab Foltabs Prenatal Plus DHA Chromease Tab Luna Vitamin and Mineral Bar for Women Mycelized Childrens Multi-vitamin Liq Children's Chewable Multiple Vit.plus Iron Ellis Tonic Multitol-M Formula Fm Vitamins & Minerals Tab One Daily VITES Vitalife - Capsule Biovim Tab Flintstones Multiple Vitamins Tab Numark Multivitamins Multi-Vitamin Fluoride Pediatric Infuvite Multiple Vitamins PreTAB Vitachrom Gc NephPlex Rx Multi-force for Women Tab Multiple Vitamins Childrens Chewable Fibrik Prenatal Supplement - Tab Super Charged Energy Materna Tricare Prenatal DHA One With Folate Trinatal Rx 1 Prefera OB plus DHA Virt-C DHA RE Nata OB Gynedyn Tab Iron Folate Plus Kids Stuff Tablets Beminal Fortis Elx Nephron FA Thrivite Rx Multi 12 Injection Ply Vi Sol Chewable Tab Lorid Ultimate Tab Ultra Hr Multivitamines Pour Enfants (chewable Tablets) Multiple Vit Plus Iron Tab WesNate DHA Multi-Vitamin With Fluoride B-50 Complex Children's Chewable Multivitamins and Minerals Multivitamines Omega-3 Rx Complete Renate DHA Nata Komplete Stress B & C Caplet Phosthenine Vitamines Et Fer (ampoules Buvable) PreferaOB plus DHA Multi Tabs Childrens Chewable Multiple Vitamins W.iron Medi Msm (methyl Sulfonyl Methane) Appedrine C-force Chewable Multiple Vitamins Plus Extra C B Complex With C 300mg Tab One A Day Advance Adults Total Living Concepts Formula One - Tab Multi-Vitamin Fluoride and Iron Drops Protect Plus SO 60 Vital Be-100 Stress Formula B-comp + 500mg Vit C Tab Vitafol Plus Multi Flow Tablets Adult Formula 50+ Vyo Cylate - Pwr Balanced B-50 Complex Multi-11 Keylosa Finazol Virt-Caps Omnivex Corvita Super Stress Capsules B-50 Complex Tab RE Nata One-A-day Advance Men's Se-Natal 19 Chewable Great Day/am Formula Tab Beminal With C Fortis Cap B Compound 50mg Tab Complexe B Compose 75 Mor-vites Tab PR Natal 400 Sopalamine/3b Tab Kaydia Patch Maxine Vitamin and Mineral Supplement Natural Source Spectrum With Beta Carotene Stress Vitamin B With C Complex Tablets Everyday Multiple Vitamins Dialyvite SetonET-EC Ventrixyl Fe Mega-vim 75 With Beta-carotene - Tablets Children Choice Multivit Chewable Tab Natal-V RX Multi-vitamin/Multi-mineral Timed Release B Complex 100 Srt Vitrexyl Vinate AZ Multi-phyto Capsules Pro His Mint Bev 29 Tab Envirocomplex Multi-Nate 30 PNV Tabs 29-1 Prenatal Mega Antioxidant Focalgin CA Multipack II FolaGent DHA One-A-day Advance Fem - Tablets Neonatal Plus Vitamin Mega Plex III - Pck Hi Potency Balanced B-100 Complex - Tab WestGel DHA Stress Formula + Iron Bev B-150 Glyco Plus Ect Hill.vite Dialyvite 5000 Megavite Rx Twin G.F. Powder Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Complexe B 75mg Spark Cap Vita-B B-50 Hi Potency B Vitamins Tab Folet DHA Tender Age Multi Vitamins Animal Shapes w/Iron Chewtabs Balanced B-100 B-complex Vitamins Tab Cavan Folate DHA Harvest Of Values All B Complex Tab Liqui Vita Multiple Vitamins and Minerals New Chapter's D'adamo 4 Your Type Multiple for Type O Prenatvite Lipovite NESTABS Prenatal Multi-vitamin/Mineral Supplement Alkadrenergy Tablets Childrens Chewab Vitamin W Chel Minerals Phytofortis + Calcium A-D Duet DHA 400 NataChew Q.T. #4 Vitamin and Mineral Dietary Supplement Vitamin B1 100mg Stress Ctr Srt Quflora FE Pediatric Drops Centratex Lipotropic Ctr OBTREX DHA Combo Pack Vigem 12 Liquid NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Wellness Formula B-plex Neonatal DHA Multivitamin with 1.0 mg Fluoride Stress B With 1000 Mg Vitamin C Kimchi Vitamin chewable multivitamin Nutrilite Double X Bugs Bunny and Friends Multiple Vitamins Multi Plex I - Tab MultiVitamin with Fluoride Chewable Omniquin Vtb Vitamin and Mineral Supplement Thiamine Hydrochloride Timed Release B-complex 50 Multiple Vitamins & Minerals Tablets TriphroCaps Puralor Sun-rype Vitaburst Mega Balance Vitrexate FE Palm Springs Multvit and Min Tab Vp-heme Ob DHA Junior Multi Vitamins - Regular Tandem Plus PreferaOB T.R.I. B-plex Src Neo Bex Elixir Vitafol OB Caplet Gtf-vitamin-minerals & Pancreatin Tab B Virol Vc II Childrens Chew Multi Vitamin Tab CitraNatal Essence Hypo Vites Tab Hylazinc Vitamines Et Mineraux Comprimes PreQue 10 Cyroplex Nephrocaps Gestamine Comprimes Formula O.C. Se-Natal One Prenatal Vitamin and Mineral Supplement -tab Hemarexin Amp Stress Tablets Vitamine Du Groupe B Plus Fer - Liq Escavite D Thiamine HCl Tab 25mg Multiple Vitamins Plus Iron Tab Chewable Children's Complete Multivitamins With Essential Minerals B-plex 100 OB Complete DHA Vitamin B Complex Suppl Venexa Low Potency B Complex Tab Acti-thiamine Caplet 100mg Balanced B-complex Vit + Vit C&e Tab Cavan-EC SOD DHA Gtf Support Caplet Multi Vitamin, Iron and Fluoride Multi-vitamin Dietary Supplement Multivitamins and Minerals for Young Men Multivitamins for Children Neo-bex PureFe OB Plus Edge OB Se-Care Conceive Multiple Vitamins With Minerals Tablets Trinatal Ultra B Plus C 300 mg MI-Vite RX Stress B Complex With C and E Tab Zyvit Vitamin B Complex Complete Natal DHA Ferra Naka Plus Vitamins M.V.I. 12 Pregvit Folic 4 Feminique W Iron and Calcium Tab Insur-all Vitamin Supplement Multivitamines Et Mineraux Infantol Drops Stress Tab With Iron and Vitamin E Zoo Chews Poly-Vi-Flor with Iron Select-OB Plus DHA Prenatal Supplement Plus DHA Poly-Vitamin with Fluoride Jenliva Q.T. Vitamin and Mineral Drink Mix Allbee With C 550 Cap Beminal W C Fortis Inj One Per Day Vitamin and Mineral Dietary Supplement Geritol Liquid Vitaday Junior Tab Prenatal Vitamin and Mineral Supplement Tab Phytoplex B Liq Chewable Multiple Vit Plus Iron for Children Dexifol Vita-vim With Beta-carotene - Tab Chewable Multivitamins Plus Iron Vit B Complex Plus Vit C 550mg One A Day Advance Adults 50+ Nutra-clear MultiVitamin, Iron and Fluoride Drops Vol-Care Rx CitraNatal 90 DHA Lexazin Corvite Garfield Chewable Multivits Plus Iron Tab Biovita Childrens Chewable Multiple Vitamins Livita Children B-complex-50 Tab Complex-75 PreNatal 19 Chewable Multiple Vitamins Tab Pretrate Vita-worth B-complex Tablets Vitafol-OB Plus DHA Prenatal Supplement Plus DHA WesNatal DHA Complete Vege 1 Daily Tab Formula Gm Dynam Ampoule Et Tablet N.E.U. Complex Multi-vitamines Enfants Comprime Triveen-Duo DHA 50 Plus Multiple Vitamins & Minerals HemeNatal OB Everyday Multiple Vitamins With Iron Gemvites Jr Tab Chewable Multi Vitamin and Mineral vitamin Swiss One Timed Release Tab Flintstones Multiple Vitamins Active FE Pregvit Folic 5 Tini-cal Ampoules Supravite Stress Avec Vit E Multi-12 Pediatric Children's Vitamins Chewable Zavitrol hormaSAN forte Children's Chewable Tab Stress B Complex With C,e, Zinc and Copper Acti-MN + B1 + C Caplet Multi Vitamines - Liq Inatal Advance Prenatvite Plus Zeldana Neo-vites & Minerals Tab Mega Vitaminerals Reaphirm Plant Source DHA Synergistic Manganese Cap Xyzbac Childrens Chewable Multiple Vitamins Tab Kanga Sport Vitamins B & C Plus Minerals PreGen DHA Kids Stuff With Iron Tablets Prenatal Vitamin and Mineral Supplement P.N.P. Vitamin Drink Maltlevol Liq B6 Plus Tab M.V.I. Pediatric Multi Vitamins & Minerals Infant Multivitamin Drops Revival 1 Tab vitaMedMD One Rx Vitamin B Complex 100 Tab Multi 1000 Children's Chewable Multivitamins With Minerals Duet DHA Balanced Infuvite Adult Cc II Pnv-VP-U Poly-VI-flor PROTECT IRON Liquid Mega 13 Multivitamin Formula Taron-C DHA Nrg Plus Liq Active OB High Potency Vitamin B Complex + C Tab K.L. Vitamin-mineral Enrich Core Pack - Children Vitamin and Mineral Supplement Virt-Nate Stress Formula Tab B-100 Complex Tablets MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement Prenatal Plus Vitamins Leritone Junior Poly-Vite Pediatric Oral Solution Davimet with Iron
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682