Lysine (abbreviated as Lys or K) is an ¦Á-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ¦Å-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ¦Å-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
6-ammonio-L-norleucine
L-Lysine
Lysina
Lysine acid
Lysine monohydrate
Lysine dihydrate
Lysine
L-2,6-Diaminocaproic acid
(S)-2,6-diaminohexanoic acid
Lysine acetate
(S)-lysine
L-Lysin
L-lys
Lysine hydrochloride
Lysinum
LYS
(S)-¦Á,¦Å-diaminocaproic acid
Brand Names
Aminosyn II 7% With 50% Dextrose
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
Aminosyn RF Injection
Vamin N
Imubolic
Renamin (amino Acids) Injection
Olimel 5.7% E
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Smofkabiven Peripheral
Travasol Amino Acid Inj 5.5%
Aminosyn II 8.5% With 50% Dextrose
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn HF
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
Aminosyn RF
Smofkabiven
Aminosyn 8.5%
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
Olimel 4.4% E
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Primene 10%
Aminosyn 5%
8.5% Freamine III
NephrAmine
Aminosyn 8.5% Injection With Electrolytes
ProSol
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
FreAmine III
TrophAmine
Olimel 7.6% E
FreAmine HBC
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Premasol - sulfite-free (Amino Acid)
Clinisol
Primene 10%-liq IV
Olimel 5.7%
Hepatasol
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Perikabiven
Aminosyn II and Dextrose
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Olimel 4.4%
Smofkabiven Extra Nitrogen
Aminosyn II in Dextrose
Nephramine Liq IV
20% Prosol
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Nutrineal Pd4
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
Aminosyn-PF
Essepna
Travasol
Travasol Inj Without Electrolytes 8.5%
Plenamine
Travasol Amino Acid Inj 8.5%
Clinimix E
Aminosyn II 7% Injection
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Aminosyn-PF 7%
RenAmin
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Aminosyn II In Dextrose Injection
Olimel 7.6%
Travasol E
Aminosyn II 8.5% Injection
Aminosyn-PF 10%
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Aminosyn II 7% With 10% Dextrose
Smofkabiven Electrolyte Free
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
HepatAmine
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
Novamine
Xyzmune
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
ProcalAmine
Aminosyn II with Electrolytes
Aminosyn II 5% Inj
Aminosyn 7%
Travasol Inj Without Electrolytes 5.5%
Aminosyn II
Olimel 3.3% E
Aminosyn
Clinimix
Aminosyn 10% W Electrolytes
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Periolimel 2.5% E
Aminosyn Sulfite Free
Primene
Vamin 18 Electrolyte-free
Aminosyn II with Electrolytes in Dextrose with Calcium
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Effervescent Potassium Chloride
Kabiven
Synthamin
Smofkabiven Extra Nitrogen Electrolyte Free
Aminosyn II 10% With Electrolytes
Lysakare
Aminosyn 3.5% M
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682