Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent.[L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986.[L31858]
Synonyms
Tranhexamic acid
Trans AMCHA
trans-Tranexamic acid
Acidum tranexamicum
Tranexamic acid
Tranexamsaeure
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
Tranexmic acid
trans-Amcha
trans-4-aminomethylcyclohexane-1-carboxylic acid
¨¢cido tranex¨¢mico
Acide tran¨¦xamique
Brand Names
Skinmd Laboratories Pure Whitenol Serum
Tranexamic Acid Injection
Lysteda
SKINMD LABORATORIES ReviTox blue
Tranexamic Acid
Cyklokapron 500 mg
Cyklokapron
Mar-tranexamic Acid
Skinmd Laboratories Pure Whitenol Intensive
Tranexamic Acid In Sodium Chloride
M-tranexamic Acid
Pure Whitenol Serum
Gd-tranexamic Acid
Liquid
Cyklokapron 100 mg/ml
Tranexamic acid
Tranexamic Acid Tablets
Tranexamic Acid Injection BP
Erfa-tranexamic
Tranexamic Acid Injection, USP
Indication
Taken orally, tranexamic acid is indicated for the treatment of hereditary angioedema,[L31883] cyclic heavy menstrual bleeding in premenopausal females,[L31858] and other instances of significant bleeding in the context of hyperfibrinolysis.[L31883] Given intravenously, tranexamic acid is indicated for short-term use (2-8 days) in patients with hemophilia to prevent or reduce bleeding following tooth extraction.[L31853]
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682