9DSX | pdb_00009dsx

Crystal structure of the complex of M. tuberculosis PheRS with cognate precursor tRNA and fragment DDD00107555

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, D	Phenylalanine--tRNA ligase alpha subunit	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding anion binding adenyl nucleotide binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding ligase activity, forming carbon-oxygen bonds aminoacyl-tRNA ligase activity catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid phenylalanine-tRNA ligase activity catalytic activity, acting on a tRNA catalytic activity ligase activity RNA binding tRNA binding nucleic acid binding	amino acid activation tRNA aminoacylation RNA metabolic process primary metabolic process amino acid metabolic process translation gene expression tRNA aminoacylation for protein translation macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process biosynthetic process metabolic process amino acid activation tRNA aminoacylation RNA metabolic process primary metabolic process amino acid metabolic process translation gene expression tRNA aminoacylation for protein translation macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process biosynthetic process metabolic process cellular process macromolecule metabolic process protein metabolic process phenylalanyl-tRNA aminoacylation	cell periphery cellular anatomical structure plasma membrane membrane intracellular anatomical structure cytoplasm
C, F	tRNA(Phe)	-	-	-
B, E	Phenylalanine--tRNA ligase beta subunit	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding anion binding adenyl nucleotide binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding ligase activity, forming carbon-oxygen bonds aminoacyl-tRNA ligase activity catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid phenylalanine-tRNA ligase activity catalytic activity, acting on a tRNA catalytic activity ligase activity RNA binding tRNA binding nucleic acid binding	amino acid activation tRNA aminoacylation RNA metabolic process primary metabolic process amino acid metabolic process translation gene expression tRNA aminoacylation for protein translation macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process biosynthetic process metabolic process amino acid activation tRNA aminoacylation RNA metabolic process primary metabolic process amino acid metabolic process translation gene expression tRNA aminoacylation for protein translation macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process biosynthetic process metabolic process cellular process macromolecule metabolic process protein metabolic process phenylalanyl-tRNA aminoacylation	cell periphery cellular anatomical structure plasma membrane membrane protein-containing complex intracellular anatomical structure catalytic complex cytoplasm phenylalanine-tRNA ligase complex external encapsulating structure cell wall peptidoglycan-based cell wall

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, D	IPR045864	Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)	Homologous Superfamily
A, D	IPR002319	Phenylalanyl-tRNA synthetase	Domain
A, D	IPR004188	Phenylalanine-tRNA ligase, class II, N-terminal	Domain
A, D	IPR004529	Phenylalanyl-tRNA synthetase, class IIc, alpha subunit	Family
A, D	IPR022911	Phenylalanine-tRNA ligase alpha chain 1, bacterial	Family
A, D	IPR006195	Aminoacyl-tRNA synthetase, class II	Domain
A, D	IPR010978	Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm	Homologous Superfamily
B, E	IPR009061	Putative DNA-binding domain superfamily	Homologous Superfamily
B, E	IPR045060	Phenylalanine-tRNA ligase, class IIc, beta subunit	Family
B, E	IPR020825	Phenylalanyl-tRNA synthetase-like, B3/B4	Homologous Superfamily
B, E	IPR045864	Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)	Homologous Superfamily
B, E	IPR002547	tRNA-binding domain	Domain
B, E	IPR005147	tRNA synthetase, B5-domain	Domain
B, E	IPR005146	B3/B4 tRNA-binding domain	Domain
B, E	IPR041616	Phenylalanyl tRNA synthetase beta chain, core domain	Domain
B, E	IPR033714	Phenylalanly tRNA synthetase, tRNA-binding-domain	Domain
B, E	IPR005121	Ferrodoxin-fold anticodon-binding domain	Domain
B, E	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
B, E	IPR036690	Ferrodoxin-fold anticodon-binding domain superfamily	Homologous Superfamily
B, E	IPR004532	Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type	Family