8QUN | pdb_00008qun

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth AAA], B [auth BBB]	Carbonic anhydrase 1	cyanamide hydratase activity hydro-lyase activity lyase activity catalytic activity carbon-oxygen lyase activity hydrolase activity, acting on ester bonds arylesterase activity carboxylic ester hydrolase activity hydrolase activity cation binding transition metal ion binding zinc ion binding ion binding binding cyanamide hydratase activity hydro-lyase activity lyase activity catalytic activity carbon-oxygen lyase activity hydrolase activity, acting on ester bonds arylesterase activity carboxylic ester hydrolase activity hydrolase activity cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding carbonate dehydratase activity	-	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle extracellular space vesicle extracellular membrane-bounded organelle

Chains	Accession	Name	Type
A [auth AAA], B [auth BBB]	IPR018338	Carbonic anhydrase, alpha-class, conserved site	Conserved Site
A [auth AAA], B [auth BBB]	IPR001148	Alpha carbonic anhydrase domain	Domain
A [auth AAA], B [auth BBB]	IPR036398	Alpha carbonic anhydrase domain superfamily	Homologous Superfamily
A [auth AAA], B [auth BBB]	IPR023561	Carbonic anhydrase, alpha-class	Family

Chains	Drug Target	Associated Disease
A [auth AAA], B [auth BBB]	Pharos: P00915	esophageal squamous cell carcinoma bagassosis pneumoconiosis adenocarcinoma tubular adenocarcinoma granular cell carcinoma MALT lymphoma open-angle glaucoma Peripheral Edema due to Chronic Heart Failure acute myeloid leukemia tuberculosis cribriform carcinoma of breast gastric cancer hereditary diffuse gastric adenocarcinoma medulloblastoma esophageal squamous cell carcinoma bagassosis pneumoconiosis adenocarcinoma tubular adenocarcinoma granular cell carcinoma MALT lymphoma open-angle glaucoma Peripheral Edema due to Chronic Heart Failure acute myeloid leukemia tuberculosis cribriform carcinoma of breast gastric cancer hereditary diffuse gastric adenocarcinoma medulloblastoma osteosarcoma angle-closure glaucoma childhood absence epilepsy gastric neoplasm lung cancer sarcoidosis ulcerative colitis cribriform carcinoma malignant colon neoplasm