Annotations: 6N4I

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
E	SCOP2B Superfamily	omega toxin-like	8082346	3000255	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	omega toxin-like	8082346	3000255	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	omega toxin-like	8082346	3000255	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	omega toxin-like	8082346	3000255	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Ion_trans	e6n4iA1	A: alpha complex topology	X: Voltage-gated ion channels (From Topology)	H: Voltage-gated ion channels (From Topology)	T: Voltage-gated ion channels	F: Ion_trans	ECOD (1.6)
B	Ion_trans	e6n4iB1	A: alpha complex topology	X: Voltage-gated ion channels (From Topology)	H: Voltage-gated ion channels (From Topology)	T: Voltage-gated ion channels	F: Ion_trans	ECOD (1.6)
C	Ion_trans	e6n4iC1	A: alpha complex topology	X: Voltage-gated ion channels (From Topology)	H: Voltage-gated ion channels (From Topology)	T: Voltage-gated ion channels	F: Ion_trans	ECOD (1.6)
D	Ion_trans	e6n4iD1	A: alpha complex topology	X: Voltage-gated ion channels (From Topology)	H: Voltage-gated ion channels (From Topology)	T: Voltage-gated ion channels	F: Ion_trans	ECOD (1.6)
E	Toxin_12	e6n4iE1	A: few secondary structure elements	X: omega toxin-like	H: omega toxin-related	T: omega toxin-related	F: Toxin_12	ECOD (1.6)
F	Toxin_12	e6n4iF1	A: few secondary structure elements	X: omega toxin-like	H: omega toxin-related	T: omega toxin-related	F: Toxin_12	ECOD (1.6)
G	Toxin_12	e6n4iG1	A: few secondary structure elements	X: omega toxin-like	H: omega toxin-related	T: omega toxin-related	F: Toxin_12	ECOD (1.6)
H	Toxin_12	e6n4iH1	A: few secondary structure elements	X: omega toxin-like	H: omega toxin-related	T: omega toxin-related	F: Toxin_12	ECOD (1.6)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Nav1.7 VSD2-NavAb channel chimera protein	-	-	-
E, F, G, H	Beta/omega-theraphotoxin-Tp2a	monoatomic cation transmembrane transporter activity channel regulator activity ion channel regulator activity monoatomic ion channel activity sodium channel activity sodium ion transmembrane transporter activity monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity channel activity molecular function regulator activity inorganic cation transmembrane transporter activity sodium channel regulator activity monoatomic ion transmembrane transporter activity transporter activity monoatomic cation transmembrane transporter activity channel regulator activity ion channel regulator activity monoatomic ion channel activity sodium channel activity sodium ion transmembrane transporter activity monoatomic cation channel activity passive transmembrane transporter activity inorganic molecular entity transmembrane transporter activity channel activity molecular function regulator activity inorganic cation transmembrane transporter activity sodium channel regulator activity monoatomic ion transmembrane transporter activity transporter activity transporter regulator activity metal ion transmembrane transporter activity transmembrane transporter activity binding lipid binding calcium channel activity calcium channel regulator activity calcium ion transmembrane transporter activity toxin activity	-	cellular anatomical structure extracellular region

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.